Two Years Postdoc Position, BMBF-BIODISC programme, Institute of Immunology, University of Heidelberg

Two Years Postdoc Position, BMBF-BIODISC programme, Institute of Immunology, University of Heidelberg

The overall objective of the BMBF-funded international collaborative project (university and industrial partners) is to enhance the understanding of the molecular mechanisms of tumor cell resistance to complement (e.g. by overexpression of membrane complement inhibitors). The project will focus on specific targeting potent siRNA to tumor cells in order to silence membrane complement regulators. This is expected to lead to sensitization of tumor cells to antibody-induced (e.g. Rituximab) complement attack and to opsonization that may also improve NK cell cytotoxicity.

The position is located at the interface between cell biology, immunology and lipid biochemistry. The applicants should have a strong background in immunology and cell and molecular biology. Knowledge of drug delivery systems (nanomedicine), a considerable background in cell culture techniques and general immunological, biochemical and molecular approaches is required. Experience in membrane and lipid biochemistry is especially welcome.

The position requires organizational qualifications and the ability to communicate effectively (in German and English) with internal and external collaborators.

We are looking for a highly motivated candidate with interests to work within an interdisciplinary team in this project of translational medicine.

We offer a work in a dedicated research team and state-of-the art equipment. The position is available immediately but may be started latest by October 1st.
Payment is according to TV-L E13.

Applications must be received latest by August 31, 2009.

Applicants should send a motivation letter, a detailed CV including certificates, publication list, and informations on methodological experiences to:

Prof. Dr. Michael Kirschfink
Institut für Immunologie
Universität Heidelberg
Im Neuenheimer Feld 305
D-69120 Heidelberg
Tel: +49 6221 56 4076/4026
Fax: +49 6221 56 5586
e-mail: kirschfink-at-uni-hd.de